Ontology highlight
ABSTRACT:
SUBMITTER: Ko CS
PROVIDER: S-EPMC6683747 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Ko Clint S CS Tserunyan Vardges V Martin Adam C AC
The Journal of cell biology 20190621 8
During development, forces transmitted between cells are critical for sculpting epithelial tissues. Actomyosin contractility in the middle of the cell apex (medioapical) can change cell shape (e.g., apical constriction) but can also result in force transmission between cells via attachments to adherens junctions. How actomyosin networks maintain attachments to adherens junctions under tension is poorly understood. Here, we discovered that microtubules promote actomyosin intercellular attachments ...[more]