Ontology highlight
ABSTRACT:
SUBMITTER: Hernandez-Candia CN
PROVIDER: S-EPMC6684405 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Hernández-Candia Carmen N CN Wysoczynski Christina L CL Tucker Chandra L CL
Methods (San Diego, Calif.) 20190321
Synthetic regulation of gene expression provides a powerful approach to reprogram molecular and cellular processes and test the function of specific genes and gene products. In the last decade, optogenetic systems that allow light-dependent gene regulation have become valuable tools, providing tight spatiotemporal control of protein levels. Here we discuss and build on recent optogenetic approaches for regulating gene expression in mammalian cells using cryptochrome 2 (CRY2), a photoreceptor pro ...[more]