Dataset Information

Comparative study of the outcome between alcohol and gallstone pancreatitis in a high-volume tertiary care center.

ABSTRACT:

Background and aim

The two most common etiologies of acute pancreatitis (AP) are alcohol and gallstone. Whether etiology contributes to the outcome in patients with AP is an unresolved issue, more so in the severe form of the disease. The aim is to study the effects of the etiological factors of alcohol and gallstone on the disease course and the role of etiology in the subgroup of severe AP.

Methods

Consecutive patients of AP with alcohol or gallstone etiology were included. Various severity parameters and various outcome measures, such as need for organ support, intensive care, surgical or radiological intervention, hospital stay, and mortality, were evaluated between the two groups.

Results

Of the 759 patients, alcoholic pancreatitis was seen in 368 (48.5%), while gallstone disease was observed in 246 (32.4%). Gallstone pancreatitis occurred in older age (P?P?P?=?0.002) compared to alcohol pancreatitis. Both groups were similar in terms of development of various organ failures and various severity assessment scores. Alcoholic AP had higher rates of necrosis (P?=?0.05) and the need for percutaneous catheter drainage (P?=?0.02). Outcome measures such as length of hospital stay, need for intensive care, organ support, surgical intervention, or mortality were similar between the two groups. Subset analysis of severe AP (303 patients) showed no difference between the two etiologies with regard to outcome.

Conclusion

The outcome of AP was independent of the etiology of the disease, alcohol or gallstone, and more so in the severe form of the disease. The number of local complications tends to be slightly higher in the alcoholic group.

SUBMITTER: Samanta J

PROVIDER: S-EPMC6684514 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature

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Publications

Comparative study of the outcome between alcohol and gallstone pancreatitis in a high-volume tertiary care center.

Samanta Jayanta J Dhaka Narendra N Gupta Pankaj P Singh Anupam K AK Yadav Thakur D TD Gupta Vikas V Sinha Saroj K SK Kochhar Rakesh R

JGH open : an open access journal of gastroenterology and hepatology 20190326 4

<h4>Background and aim</h4>The two most common etiologies of acute pancreatitis (AP) are alcohol and gallstone. Whether etiology contributes to the outcome in patients with AP is an unresolved issue, more so in the severe form of the disease. The aim is to study the effects of the etiological factors of alcohol and gallstone on the disease course and the role of etiology in the subgroup of severe AP.<h4>Methods</h4>Consecutive patients of AP with alcohol or gallstone etiology were included. Vari ...[more]

PMID: 31406928

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Dataset Information

Comparative study of the outcome between alcohol and gallstone pancreatitis in a high-volume tertiary care center.

Background and aim

Methods

Results

Conclusion

Publications

Comparative study of the outcome between alcohol and gallstone pancreatitis in a high-volume tertiary care center.

Similar Datasets

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