Ontology highlight
ABSTRACT:
SUBMITTER: Cao Z
PROVIDER: S-EPMC6684626 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Cao Zhenping Z Cheng Shanshan S Wang Xinyue X Pang Yan Y Liu Jinyao J
Nature communications 20190806 1
Bacteria have been extensively utilized for bioimaging, diagnosis and therapy given their unique characteristics including genetic manipulation, rapid proliferation and disease site targeting specificity. However, clinical translation of bacteria for these applications has been largely restricted by their unavoidable side effects and low treatment efficacies. Engineered bacteria for biomedical applications ideally need to generate only a low inflammatory response, show slow elimination by macrop ...[more]