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Case Report: Coinfection with Rickettsia monacensis and Orientia tsutsugamushi.

ABSTRACT: Rickettsia monacensis and Orientia tsutsugamushi are bacteria of the family Rickettsiaceae, which causes fever, rash, and eschar formation; outdoor activities are a risk factor for Rickettsiaceae infection. A 75-year-old woman presented with fever, rash, and eschar and was confirmed as being scrub typhus based on a nested-polymerase chain reaction (N-PCR) test for a 56-kDa gene of O. tsutsugamushi; the genome was identified as the Boryong genotype. In addition, a pan-Rickettsia real-time PCR test was positive and a N-PCR test using a Rickettsia-specific partial outer membrane protein A (rOmpA) confirmed R. monacensis. This is the first case wherein a patient suspected of having scrub typhus owing to the presence of rash and eschar was also found to be coinfected with O. tsutsugamushi and R. monacensis based on molecular testing.

SUBMITTER: Kim SW

PROVIDER: S-EPMC6685553 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature

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Case Report: Coinfection with Rickettsia monacensis and Orientia tsutsugamushi.

Kim Seok Won SW Kim Choon-Mee CM Kim Dong-Min DM Yun Na Ra NR

The American journal of tropical medicine and hygiene 20190801 2

Rickettsia monacensis and Orientia tsutsugamushi are bacteria of the family Rickettsiaceae, which causes fever, rash, and eschar formation; outdoor activities are a risk factor for Rickettsiaceae infection. A 75-year-old woman presented with fever, rash, and eschar and was confirmed as being scrub typhus based on a nested-polymerase chain reaction (N-PCR) test for a 56-kDa gene of O. tsutsugamushi; the genome was identified as the Boryong genotype. In addition, a pan-Rickett ...[more]

PMID: 31219004

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