Ontology highlight
ABSTRACT:
SUBMITTER: Clarke EV
PROVIDER: S-EPMC6685685 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Clarke Elizabeth V EV Muessig Kristin R KR Zepp Jamilyn J Hunter Jessica E JE Syngal Sapna S Acheson Louise S LS Wiesner Georgia L GL Peterson Susan K SK Bergen Kellene M KM Shuster Elizabeth E Davis James V JV Schneider Jennifer L JL Kauffman Tia L TL Gilmore Marian J MJ Reiss Jacob A JA Rope Alan F AF Cook Jennifer E JE Goddard Katrina A B KAB
Familial cancer 20190701 3
A subset of colorectal cancer (CRC) cases are attributable to Lynch syndrome (LS), a hereditary form of CRC. Effective evaluation for LS can be done on CRC tumors to guide diagnostic testing. Increased diagnosis of LS allows for surveillance and risk reduction, which can mitigate CRC-related burden and prevent cancer-related deaths. We evaluated participation in LS screening among newly diagnosed adult CRC patients. Some cases were referred for genetics evaluation prior to study recruitment (sel ...[more]