Ontology highlight
ABSTRACT:
SUBMITTER: Hirad AA
PROVIDER: S-EPMC6685720 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Hirad Adnan A AA Bazarian Jeffrey J JJ Merchant-Borna Kian K Garcea Frank E FE Heilbronner Sarah S Paul David D Hintz Eric B EB van Wijngaarden Edwin E Schifitto Giovanni G Wright David W DW Espinoza Tamara R TR Mahon Bradford Z BZ
Science advances 20190807 8
The midbrain is biomechanically susceptible to force loading from repetitive subconcussive head impacts (RSHI), is a site of tauopathy in chronic traumatic encephalopathy (CTE), and regulates functions (e.g., eye movements) often disrupted in concussion. In a prospective longitudinal design, we demonstrate there are reductions in midbrain white matter integrity due to a single season of collegiate football, and that the amount of reduction in midbrain white matter integrity is related to the amo ...[more]