Aerobic Plus Resistance Exercise in Obese Older Adults Improves Muscle Protein Synthesis and Preserves Myocellular Quality Despite Weight Loss.
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ABSTRACT:
SUBMITTER: Colleluori G
PROVIDER: S-EPMC6685749 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
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Aerobic Plus Resistance Exercise in Obese Older Adults Improves Muscle Protein Synthesis and Preserves Myocellular Quality Despite Weight Loss.
Colleluori Georgia G Aguirre Lina L Phadnis Uma U Fowler Kenneth K Armamento-Villareal Reina R Sun Zheng Z Brunetti Lorenzo L Hyoung Park Jun J Kaipparettu Benny Abraham BA Putluri Nagireddy N Auetumrongsawat Vimlin V Yarasheski Kevin K Qualls Clifford C Villareal Dennis T DT
Cell metabolism 20190703 2
Anabolic resistance and impaired myocellular quality contribute to age-related sarcopenia, which exacerbates with obesity. Diet-induced muscle mass loss is attenuated by resistance or aerobic plus resistance exercise compared to aerobic exercise in obese elderly. We assessed chronic effects of weight loss plus different exercise modalities on muscle protein synthesis response to feeding and myocellular quality. Obese older adults were randomized to a weight-management program plus aerobic, resis ...[more]
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