Ontology highlight
ABSTRACT:
SUBMITTER: Li R
PROVIDER: S-EPMC6685968 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Nature communications 20190807 1
Poly-substituted aromatic sulfur compounds are widely found in pharmaceuticals, agrochemicals and organic materials. However, the position that a sulfur moiety can be introduced to is largely restricted to a pre-functionalized site; otherwise, use of electronically biased substrates or auxiliary groups that direct catalysis is required. Here we report a general ortho thiolation of common aryl and heteroaryl iodides via palladium-norbornene cooperative catalysis. Using this approach, an aryl or a ...[more]