Ontology highlight
ABSTRACT:
SUBMITTER: Vesterinen HM
PROVIDER: S-EPMC6688630 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Vesterinen Hanna M HM Johnson Paula I PI Atchley Dylan S DS Sutton Patrice P Lam Juleen J Zlatnik Marya G MG Sen Saunak S Woodruff Tracey J TJ
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 20150904 18
<h4>Objective</h4>Glomerular filtration rate (GFR) may influence concentrations of biomarkers of exposure and their etiologic significance in observational studies of associations between environmental contaminants and fetal growth. It is unknown whether the size of a developing fetus affects maternal GFR such that a small fetus leads to reduced plasma volume expansion (PVE), reduced GFR and subsequent higher concentrations of biomarkers in maternal serum. Our objective was to answer the questio ...[more]