White matter development in infants at risk for schizophrenia.
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ABSTRACT:
SUBMITTER: Ahn SJ
PROVIDER: S-EPMC6689450 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Publications
White matter development in infants at risk for schizophrenia.
Ahn Sung Jun SJ Cornea Emil E Murphy Veronica V Styner Martin M Jarskog L Fredrik LF Gilmore John H JH
Schizophrenia research 20190608
<h4>Background</h4>Schizophrenia is considered a neurodevelopmental disorder with a pathophysiology that likely begins long before the onset of clinical symptoms. White matter abnormalities have been observed in schizophrenia and we hypothesized that the first 2 years of life is a period in which white matter abnormalities associated with schizophrenia risk may emerge.<h4>Methods</h4>38 infants at high risk for schizophrenia and 202 healthy controls underwent diffusion tensor MRIs after birth an ...[more]
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