Escherichia coli belonging to ST131 rarely transfers bla _ctx-m-15 to fecal Escherichia coli.

ABSTRACT:

Background

Extended spectrum beta-lactamase (ESBL)-producing Escherichia coli (E. coli) causing urinary tract infections often belong to sequence type 131 (ST131), serotype O25, carrying bla _CTX-M-15.

Aim

The main aim of this study was to examine the conjugational frequencies of E. coli with plasmids carrying bla _CTX-M-15 to E. coli isolates from the fecal flora of healthy humans to determine whether ST131 is more likely to uptake or donate ESBL resistance compared to other E. coli clones.

Methods

 Donors and recipients were all clinical isolates and did not harbor plasmids with identical incompatibility groups (Inc-groups) based on in silico analyses of Inc-groups and restriction/modification syst

SUBMITTER: Thingholm KR 

PROVIDER: S-EPMC6689528 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature