Novel Regulators and Targets of Redox Signaling in Pulmonary Vasculature.
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ABSTRACT:
SUBMITTER: Daneva Z
PROVIDER: S-EPMC6690609 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Publications
Novel Regulators and Targets of Redox Signaling in Pulmonary Vasculature.
Daneva Zdravka Z Laubach Victor E VE Sonkusare Swapnil K SK
Current opinion in physiology 20190509
Dysregulated redox signaling in pulmonary vasculature is central to the development of pulmonary arterial hypertension (PAH) and lung injury. Modulators of reactive oxygen species (ROS) production and downstream signaling targets are critical for mediating the physiological or pathological effects of ROS. Understanding the complex interactions between the modulators and signaling targets of ROS is essential for developing novel strategies to prevent or attenuate lung pathologies. In this review, ...[more]
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