Serum uromodulin is associated with urinary albumin excretion in adolescents with type 1 diabetes.
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ABSTRACT:
SUBMITTER: Wiromrat P
PROVIDER: S-EPMC6690747 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
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Serum uromodulin is associated with urinary albumin excretion in adolescents with type 1 diabetes.
Wiromrat Pattara P Bjornstad Petter P Roncal Carlos C Pyle Laura L Johnson Richard J RJ Cherney David Z DZ Lipina Tyler T Bishop Franziska F Maahs David M DM Wadwa R Paul RP
Journal of diabetes and its complications 20190603 9
Early diabetic kidney disease (DKD) occurs in adolescents with type 1 diabetes (T1D). Lower serum uromodulin (SUMOD) predicts DKD progression in adults with T1D. In this study, we demonstrate that lower SUMOD is associated with urinary albumin excretion in adolescents with T1D, suggesting a potential relationship between SUMOD and early kidney dysfunction in T1D youth. ...[more]
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