Gestational age at birth and mortality from infancy into mid-adulthood: a national cohort study.

ABSTRACT:

Background

Breakthroughs in the treatment of preterm birth approximately 40 years ago have enabled a generation of preterm survivors to now reach mid-adulthood. Understanding their health sequelae is essential for guiding their long-term care. We did a study to examine preterm birth in relation to mortality into mid-adulthood.

Methods

A national cohort study was done of all 4 296 814 singleton livebirths in Sweden between 1973 and 2015, who were followed up for mortality through Dec 31, 2017 (maximum age 45 years). Cox regression was used to examine gestational age at birth in relation to all-cause and cause-specific mortality, and cosibling analyses assessed for potential confounding by shared familial (genetic or environmental) factors.

Findings

In 103·5 million per

SUBMITTER: Crump C 

PROVIDER: S-EPMC6691360 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature