Ontology highlight
ABSTRACT:
SUBMITTER: Forde BM
PROVIDER: S-EPMC6692316 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Nature communications 20190813 1
Recurrent urinary tract infections (rUTIs) are extremely common, with ~ 25% of all women experiencing a recurrence within 1 year of their original infection. Escherichia coli ST131 is a globally dominant multidrug resistant clone associated with high rates of rUTI. Here, we show the dynamics of an ST131 population over a 5-year period from one elderly woman with rUTI since the 1970s. Using whole genome sequencing, we identify an indigenous clonal lineage (P1A) linked to rUTI and persistence in t ...[more]