Ontology highlight
ABSTRACT:
SUBMITTER: Manasa KL
PROVIDER: S-EPMC6693371 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Beilstein journal of organic chemistry 20190805
An efficient, simple, and metal-free synthetic approach for the <i>N</i>- and <i>O</i>-benzoylation of various amines/benzyl alcohols with pyridinium salts of phenacyl bromides is demonstrated to generate the corresponding amides and esters. This protocol facilitates the oxidative cleavage of a C-C bond followed by formation of a new C-N/C-O bond in the presence of K<sub>2</sub>CO<sub>3</sub>. Various pyridinium salts of phenacyl bromides can be readily transformed into a variety of amides and e ...[more]