Ontology highlight
ABSTRACT:
SUBMITTER: Drews HJ
PROVIDER: S-EPMC6694377 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Drews Henning J HJ Yenkoyan Konstantin K Lourhmati Ali A Buadze Marine M Kabisch Daniela D Verleysdonk Stephan S Petschak Stefan S Beer-Hammer Sandra S Davtyan Tigran T Frey William H WH Gleiter Christoph H CH Schwab Matthias M Danielyan Lusine L
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20190701 3
The contribution of the local angiotensin receptor system to neuroinflammation, impaired neurogenesis, and amyloid beta (Aβ) accumulation in Alzheimer's disease (AD) and in hypertension is consistent with the remarkable neuroprotection provided by angiotensin receptor blockers (ARBs) independent of their blood pressure-lowering effect. Considering the causal relationship between hypertension and AD and that targeting cerebrovascular pathology with ARBs does not necessarily require their systemic ...[more]