Ontology highlight
ABSTRACT:
SUBMITTER: Zolla-Pazner S
PROVIDER: S-EPMC6694814 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Journal of virology 20190813 17
The RV144 vaccine trial is the only clinical study to have shown a modest but statistically significant decrease in HIV infection risk. RV144 and the subsequent studies identifying the level of V1V2-specific antibodies as a correlate of reduced infection risk are still controversial despite many papers supporting and expanding the initial study. We address these controversies and summarize active-immunization and passive-immunization experiments in nonhuman primates that support the initial find ...[more]