Ontology highlight
ABSTRACT:
SUBMITTER: Yoshinari GH
PROVIDER: S-EPMC6695187 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Yoshinari Gerson Hiroshi GH Fassoni Artur César AC Mello Luis Fernando LF Rego Eduardo M EM
PloS one 20190815 8
Acute Promyelocytic Leukemia (APL) is a rare and potentially lethal condition in which risk-based therapy often leads to better outcomes. Because of its rarity and relatively high overall survival rate, prospective randomized trials to investigate alternative APL treatment schedules are challenging. Mathematical models may provide useful information in this regard. We collected clinical data from 38 patients treated for APL under the International Consortium on Acute Leukemia (ICAL) protocol and ...[more]