Ontology highlight
ABSTRACT:
SUBMITTER: Huang BZ
PROVIDER: S-EPMC6697114 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Huang Brian Z BZ Tsilidis Konstantinos K KK Smith Michael W MW Hoffman-Bolton Judith J Visvanathan Kala K Platz Elizabeth A EA Joshu Corinne E CE
Molecular carcinogenesis 20180605 10
We previously investigated the association between single nucleotide polymorphisms (SNPs) in genes related to obesity and inflammation and colorectal cancer in the CLUE II cohort. However, the relationships between these SNPs and colorectal adenomas have not been well evaluated. In a nested case-control study of 135 incident adenoma cases and 269 matched controls in the CLUE II cohort (1989-2000), we genotyped 17 candidate SNPs in 12 genes (PPARG, TCF7L2, ADIPOQ, LEP, IL10, CRP, TLR4, IL6, IL1B, ...[more]