Ontology highlight
ABSTRACT:
SUBMITTER: Ziesack M
PROVIDER: S-EPMC6697442 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Ziesack Marika M Gibson Travis T Oliver John K W JKW Shumaker Andrew M AM Hsu Bryan B BB Riglar David T DT Giessen Tobias W TW DiBenedetto Nicholas V NV Bry Lynn L Way Jeffrey C JC Silver Pamela A PA Gerber Georg K GK
mSystems 20190813 4
In nature, microbes interact antagonistically, neutrally, or beneficially. To shed light on the effects of positive interactions in microbial consortia, we introduced metabolic dependencies and metabolite overproduction into four bacterial species. While antagonistic interactions govern the wild-type consortium behavior, the genetic modifications alleviated antagonistic interactions and resulted in beneficial interactions. Engineered cross-feeding increased population evenness, a component of ec ...[more]