Ontology highlight
ABSTRACT:
SUBMITTER: Donatelli G
PROVIDER: S-EPMC6698695 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
NeuroImage. Clinical 20190715
The decline of voluntary bulbar functions such as speech and swallowing are among the clinical manifestations of amyotrophic lateral sclerosis (ALS) influencing a worst prognosis. Differential diagnosis between the contribution of upper motor neuron (UMN) and lower motor neuron degeneration to the bulbar impairment is often hard. Thinning and T2* hypointensity of the primary motor cortex have been recently suggested as possible MRI markers of UMN impairment in ALS patients, but little research h ...[more]