Ontology highlight
ABSTRACT:
SUBMITTER: Srivastava AK
PROVIDER: S-EPMC6699094 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Protein science : a publication of the Protein Society 20190806 9
In this article, we consider the role of heterogeneous nucleation in β-amyloid aggregation. Heterogeneous nucleation is more common and occurs at lower levels of supersaturation than homogeneous nucleation. The nucleation period is also the stage at which most of the polymorphism of amyloids arises, this being one of the defining features of amyloids. We focus on several well-known heterogeneous nucleators of β-amyloid, including lipid surfaces, especially those enriched in gangliosides and chol ...[more]