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Statins versus placebo for people with chronic obstructive pulmonary disease.


ABSTRACT:

SUBMITTER: Walsh A 

PROVIDER: S-EPMC6699658 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature

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Statins versus placebo for people with chronic obstructive pulmonary disease.

Walsh Aisling A   Perrem Lucy L   Khashan Ali S AS   Henry Michael T MT   Ni Chroinin Muireann M  

The Cochrane database of systematic reviews 20190731


<h4>Background</h4>Chronic obstructive pulmonary disease (COPD) is a common, preventable, and treatable respiratory disease. COPD exacerbations are associated with worse quality of life, increased hospitalisations, and increased mortality. Currently available pharmacological interventions have variable impact on exacerbation frequency. The anti-inflammatory effects of statins may lead to decreased pulmonary and systemic inflammation, resulting in fewer exacerbations of COPD. Several observationa  ...[more]

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