Ontology highlight
ABSTRACT:
SUBMITTER: Denisov SS
PROVIDER: S-EPMC6699855 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Denisov Stepan S SS Ippel Johannes H JH Heinzmann Alexandra C A ACA Koenen Rory R RR Ortega-Gomez Almudena A Soehnlein Oliver O Hackeng Tilman M TM Dijkgraaf Ingrid I
The Journal of biological chemistry 20190624 33
Chemokines are a group of chemotaxis proteins that regulate cell trafficking and play important roles in immune responses and inflammation. Ticks are blood-sucking parasites that secrete numerous immune-modulatory agents in their saliva to evade host immune responses. Evasin-3 is a small salivary protein that belongs to a class of chemokine-binding proteins isolated from the brown dog tick, <i>Rhipicephalus sanguineus</i> Evasin-3 has been shown to have a high affinity for chemokines CXCL1 and C ...[more]