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Regular exercise improves asthma control in adults: A randomized controlled trial.

ABSTRACT: We conducted a randomized controlled trial to test the hypothesis that a 24-week exercise intervention improves asthma control in adults. Adults with mild or moderate asthma were randomly assigned to either the exercise intervention group (IG) or the reference group (RG). Participants in IG received an individualized exercising program, including aerobic exercise at least three times a week for ?30?minutes, muscle training, and stretching. The primary outcome was asthma control, measured by Asthma Control Test (ACT), asthma-related symptoms, and peak expiratory flow (PEF) variability. We estimated the risk (i.e. probability) of improvement in asthma control and the risk difference (RD) between IG and RG. Of 131 subjects (67 IG/64 RG) entered, 105 subjects (51/54) completed the trial (80%), and 89 (44/45) were analysed (68%). The ACT became better among 26 (62%) participants in IG and among 17 (39%) participants in RG. The effect of intervention on improving asthma control was 23% (RD?=?0.23, 95% CI 0.027-0.438; P?=?0.0320). The intervention also reduced shortness of breath by 30.1% (RD?=?0.301, 95% CI 0.109-0.492; P?=?0.003). The change in PEF variability was similar in both groups. Regular exercise improves asthma control measured by the ACT, while has little effect on PEF variability.

SUBMITTER: Jaakkola JJK

PROVIDER: S-EPMC6700123 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature

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Regular exercise improves asthma control in adults: A randomized controlled trial.

Jaakkola Jouni J K JJK Aalto Sirpa A M SAM Hernberg Samu S Kiihamäki Simo-Pekka SP Jaakkola Maritta S MS

Scientific reports 20190819 1

We conducted a randomized controlled trial to test the hypothesis that a 24-week exercise intervention improves asthma control in adults. Adults with mild or moderate asthma were randomly assigned to either the exercise intervention group (IG) or the reference group (RG). Participants in IG received an individualized exercising program, including aerobic exercise at least three times a week for ≥30 minutes, muscle training, and stretching. The primary outcome was asthma control, measured by Asth ...[more]

PMID: 31427628

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Regular exercise improves asthma control in adults: A randomized controlled trial.

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Regular exercise improves asthma control in adults: A randomized controlled trial.

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