Dataset Information

Maintain Your Brain: Protocol of a 3-Year Randomized Controlled Trial of a Personalized Multi-Modal Digital Health Intervention to Prevent Cognitive Decline Among Community Dwelling 55 to 77 Year Olds.

ABSTRACT:

Background

Maintain Your Brain (MYB) is a randomized controlled trial of an online multi-modal lifestyle intervention targeting modifiable dementia risk factors with its primary aim being to reduce cognitive decline in an older age cohort.

Methods

MYB aims to recruit 8,500 non-demented community dwelling 55 to 77 year olds from the Sax Institute's 45 and Up Study in New South Wales, Australia. Participants will be screened for risk factors related to four modules that comprise the MYB intervention: physical activity, nutrition, mental health, and cognitive training. Targeting risk factors will enable interventions to be personalized so that participants receive the most appropriate modules. MYB will run for three years and up to four modules will be delivered sequentially each quarter during year one. Upon completing a module, participants will continue to receive less frequent booster activities for their eligible modules (except for the mental health module) until the end of the trial.

Discussion

MYB will be the largest internet-based trial to attempt to prevent cognitive decline and potentially dementia. If successful, MYB will provide a model for not just effective intervention among older adults, but an intervention that is scalable for broad use.

SUBMITTER: Heffernan M

PROVIDER: S-EPMC6700632 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Maintain Your Brain: Protocol of a 3-Year Randomized Controlled Trial of a Personalized Multi-Modal Digital Health Intervention to Prevent Cognitive Decline Among Community Dwelling 55 to 77 Year Olds.

Heffernan Megan M Andrews Gavin G Fiatarone Singh Maria A MA Valenzuela Michael M Anstey Kaarin J KJ Maeder Anthony J AJ McNeil John J Jorm Louisa L Lautenschlager Nicola T NT Sachdev Perminder S PS Ginige Jeewani A JA Hobbs Megan J MJ Boulamatsis Christos C Chau Tiffany T Cobiac Lynne L Cox Kay L KL Daniel Kenneth K Flood Victoria M VM Guerrero Yareni Y Gunn Jane J Jain Nidhi N Kochan Nicole A NA Lampit Amit A Mavros Yorgi Y Meiklejohn Jacinda J Noble Yian Y O'Leary Fiona F Radd-Vagenas Sue S Walton Courtney C CC Brodaty Henry H

Journal of Alzheimer's disease : JAD 20190101 s1

<h4>Background</h4>Maintain Your Brain (MYB) is a randomized controlled trial of an online multi-modal lifestyle intervention targeting modifiable dementia risk factors with its primary aim being to reduce cognitive decline in an older age cohort.<h4>Methods</h4>MYB aims to recruit 8,500 non-demented community dwelling 55 to 77 year olds from the Sax Institute's 45 and Up Study in New South Wales, Australia. Participants will be screened for risk factors related to four modules that comprise the ...[more]

PMID: 30475762

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Dataset Information

Maintain Your Brain: Protocol of a 3-Year Randomized Controlled Trial of a Personalized Multi-Modal Digital Health Intervention to Prevent Cognitive Decline Among Community Dwelling 55 to 77 Year Olds.

Background

Methods

Discussion

Publications

Maintain Your Brain: Protocol of a 3-Year Randomized Controlled Trial of a Personalized Multi-Modal Digital Health Intervention to Prevent Cognitive Decline Among Community Dwelling 55 to 77 Year Olds.

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