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The Delta Neutrophil Index Predicts the Development of In-hospital Hypotension in Initially Stable Patients with Pyogenic Liver Abscess.


ABSTRACT: Prompt diagnosis and timely treatment are important for reducing morbidity and mortality from pyogenic liver abscess (PLA). The purpose of this study was to investigate the importance of the delta neutrophil index (DNI) reflecting the fraction of immature granulocytes as a predictor of the development of in-hospital hypotension in initially stable patients with PLA. We retrospectively identified 308 consecutive patients (>18 years) who were hemodynamically stable at presentation and diagnosed with PLA in the emergency department (ED) between January 2011 and September 2017. The outcome of interest was in-hospital hypotension 1-24?hours after admission to the ED. A high DNI at ED admission was an independent predictor of the development of in-hospital hypotension in initially stable patients with PLA (odds ratio [OR]: 1.44, 95.0% confidence interval [CI]: 1.06-1.95; P?=?0.02). A DNI?>?3.3% was associated with in-hospital hypotension at ED admission (OR: 5.37, 95.0% CI: 2.91-9.92; P?

SUBMITTER: Kong T 

PROVIDER: S-EPMC6702230 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature

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The Delta Neutrophil Index Predicts the Development of In-hospital Hypotension in Initially Stable Patients with Pyogenic Liver Abscess.

Kong Taeyoung T   Park Yoo Seok YS   Lee Hye Sun HS   Kim Sinae S   Lee Jong Wook JW   You Je Sung JS   Chung Hyun Soo HS   Park Incheol I   Chung Sung Phil SP  

Scientific reports 20190820 1


Prompt diagnosis and timely treatment are important for reducing morbidity and mortality from pyogenic liver abscess (PLA). The purpose of this study was to investigate the importance of the delta neutrophil index (DNI) reflecting the fraction of immature granulocytes as a predictor of the development of in-hospital hypotension in initially stable patients with PLA. We retrospectively identified 308 consecutive patients (>18 years) who were hemodynamically stable at presentation and diagnosed wi  ...[more]

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