Ontology highlight
ABSTRACT:
SUBMITTER: Alldred MJ
PROVIDER: S-EPMC6704451 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Alldred Melissa J MJ Chao Helen M HM Lee Sang Han SH Beilin Judah J Powers Brian E BE Petkova Eva E Strupp Barbara J BJ Ginsberg Stephen D SD
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20190610 9
Choline is critical for normative function of 3 major pathways in the brain, including acetylcholine biosynthesis, being a key mediator of epigenetic regulation, and serving as the primary substrate for the phosphatidylethanolamine <i>N</i>-methyltransferase pathway. Sufficient intake of dietary choline is critical for proper brain function and neurodevelopment. This is especially important for brain development during the perinatal period. Current dietary recommendations for choline intake were ...[more]