Ontology highlight
ABSTRACT:
SUBMITTER: Celis AI
PROVIDER: S-EPMC6706330 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Current opinion in structural biology 20190222
Mechanisms for making and breaking the heme b cofactor (heme) are more diverse than previously expected. Biosynthetic pathways have diverged at least twice along taxonomic lines, reflecting differences in membrane organization and O<sub>2</sub> utilization among major groups of organisms. At least three families of heme degradases are now known, again differing in whether and how O<sub>2</sub> is used by the organism and possibly the purpose for turning over the tetrapyrrole. Understanding these ...[more]