Longitudinal time course of muscle impairments during partial weight-bearing in rats.
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ABSTRACT:
SUBMITTER: Mortreux M
PROVIDER: S-EPMC6706399 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Publications
Longitudinal time course of muscle impairments during partial weight-bearing in rats.
Mortreux Marie M Ko Frank C FC Riveros Daniela D Bouxsein Mary L ML Rutkove Seward B SB
NPJ microgravity 20190822
In the near future, space agencies plan to send the first crews for extended stays on the Moon and Mars, where gravity is significantly reduced compared to Earth (0.16×<i>g</i> and 0.38×<i>g</i>, respectively). However, the long-term effects of partial gravity have not yet been elucidated, and ensuring astronauts' health and performance is crucial to the success of these missions. Using a quadrupedal partial weight-bearing (PWB) model in rats that we designed, we investigated the longitudinal ti ...[more]
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