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Non-Pulmonary Vein Triggers of Atrial Fibrillation Are Likely to Arise from Low-Voltage Areas in the Left Atrium.

ABSTRACT: The pathophysiology of non-pulmonary vein (PV) triggers of atrial fibrillation (AF) is unclear. We hypothesized that left atrial non-PV (LANPV) triggers are associated with atrial tissue degeneration. This study analyzed 431 patients that underwent catheter ablation (mean age 62?yrs, 303 men, 255 paroxysmal AF [pAF] patients). Clinical and electrophysiological characteristics of non-PV trigger were analyzed. Fifty non-PV triggers in 40 patients (9.3%) were documented; LANPV triggers were the most prevalent (n?=?19, 38%). LANPV triggers were correlated with non-paroxysmal AF (non-pAF) (OR 3.31, p?=?0.04) whereas right atrial non-PV (RANPV) triggers (n?=?14) and SVC triggers (n?=?17) were not. The voltage at the LANPV sites during SR was 0.3?±?0.16?mV (p?

SUBMITTER: Kawai S

PROVIDER: S-EPMC6706423 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature

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Non-Pulmonary Vein Triggers of Atrial Fibrillation Are Likely to Arise from Low-Voltage Areas in the Left Atrium.

Kawai Shunsuke S Mukai Yasushi Y Inoue Shujiro S Yakabe Daisuke D Nagaoka Kazuhiro K Sakamoto Kazuo K Takase Susumu S Chishaki Akiko A Tsutsui Hiroyuki H

Scientific reports 20190822 1

The pathophysiology of non-pulmonary vein (PV) triggers of atrial fibrillation (AF) is unclear. We hypothesized that left atrial non-PV (LANPV) triggers are associated with atrial tissue degeneration. This study analyzed 431 patients that underwent catheter ablation (mean age 62 yrs, 303 men, 255 paroxysmal AF [pAF] patients). Clinical and electrophysiological characteristics of non-PV trigger were analyzed. Fifty non-PV triggers in 40 patients (9.3%) were documented; LANPV triggers were the mos ...[more]

PMID: 31439861

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Project description: Not available

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2020-11-14 | GSE161450 | GEO

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Cardiac computed tomography angiography-derived analysis of left atrial appendage morphology and left atrial dimensions for the prediction of atrial fibrillation recurrence after pulmonary vein isolation.

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