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Atom transfer radical polymer-modified paper for improvement in protein fixation in paper-based ELISA.

ABSTRACT: A newly modified paper-based enzyme-linked immunosorbent assay (P-ELISA) was established by immobilizing more proteins on the paper surface through an atom transfer radical polymerization (ATRP) reaction. In addition, introducing graphene oxide (GO) sheets, Au nanoparticles (AuNps) and two primary antibodies (Ab1s) led to signal amplification and cost reduction.

SUBMITTER: Qi L

PROVIDER: S-EPMC6706939 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature

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Atom transfer radical polymer-modified paper for improvement in protein fixation in paper-based ELISA.

Qi Lu L Zhang Aihong A Wang Yu Y Liu Long L Wang Xinghe X

BMC chemistry 20190822 1

A newly modified paper-based enzyme-linked immunosorbent assay (P-ELISA) was established by immobilizing more proteins on the paper surface through an atom transfer radical polymerization (ATRP) reaction. In addition, introducing graphene oxide (GO) sheets, Au nanoparticles (AuNps) and two primary antibodies (Ab1s) led to signal amplification and cost reduction. ...[more]

PMID: 31463479

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