Ontology highlight
ABSTRACT:
SUBMITTER: Pacifici M
PROVIDER: S-EPMC6707746 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Expert opinion on orphan drugs 20180607 6
<h4>Introduction</h4>Hereditary multiple exostoses (HME) is a rare congenital pediatric disorder characterized by osteochondromas forming next to the growth plates in young patients. The osteochondromas cause multiple health problems that include skeletal deformities and chronic pain. Surgery is used to remove the most symptomatic osteochondromas but because of their large number, many are left in place, causing life-long problems and increasing the probability of malignant transformation. There ...[more]