Ontology highlight
ABSTRACT:
SUBMITTER: Bleicken S
PROVIDER: S-EPMC6709561 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Bleicken Stephanie S Assafa Tufa E TE Zhang Hui H Elsner Christina C Ritsch Irina I Pink Maren M Rajca Suchada S Jeschke Gunnar G Rajca Andrzej A Bordignon Enrica E
ChemistryOpen 20190514 8
The availability of bioresistant spin labels is crucial for the optimization of site-directed spin labeling protocols for EPR structural studies of biomolecules in a cellular context. As labeling can affect proteins' fold and/or function, having the possibility to choose between different spin labels will increase the probability to produce spin-labeled functional proteins. Here, we report the synthesis and characterization of iodoacetamide- and maleimide-functionalized spin labels based on the ...[more]