Ontology highlight
ABSTRACT:
SUBMITTER: Balbi B
PROVIDER: S-EPMC6709647 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Balbi Bruno B Sangiorgi Claudia C Gnemmi Isabella I Ferrarotti Ilaria I Vallese Davide D Paracchini Elena E Delle Donne Lorena L Corda Luciano L Baderna Paolo P Corsico Angelo A Carone Mauro M Brun Paola P Cappello Francesco F Ricciardolo Fabio Lm FL Ruggeri Paolo P Mumby Sharon S Adcock Ian M IM Caramori Gaetano G Di Stefano Antonino A
International journal of chronic obstructive pulmonary disease 20190821
<h4>Background</h4>Airway inflammation may drive the progression of chronic obstructive pulmonary disease (COPD) associated with alpha-1 antitrypsin deficiency (AATD), but the relationship between airway microbiota and inflammation has not been investigated.<h4>Methods</h4>We studied 21 non-treated AATD (AATD-noT) patients, 20 AATD-COPD patients under augmentation therapy (AATD-AT), 20 cigarette smoke-associated COPD patients, 20 control healthy smokers (CS) and 21 non-smokers (CON) with normal ...[more]