Ontology highlight
ABSTRACT:
SUBMITTER: Budelli G
PROVIDER: S-EPMC6709853 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Budelli Gonzalo G Ni Lina L Berciu Cristina C van Giesen Lena L Knecht Zachary A ZA Chang Elaine C EC Kaminski Benjamin B Silbering Ana F AF Samuel Aravi A Klein Mason M Benton Richard R Nicastro Daniela D Garrity Paul A PA
Neuron 20190114 4
Thermosensation is critical for avoiding thermal extremes and regulating body temperature. While thermosensors activated by noxious temperatures respond to hot or cold, many innocuous thermosensors exhibit robust baseline activity and lack discrete temperature thresholds, suggesting they are not simply warm and cool detectors. Here, we investigate how the aristal Cold Cells encode innocuous temperatures in Drosophila. We find they are not cold sensors but cooling-activated and warming-inhibited ...[more]