Ontology highlight
ABSTRACT:
SUBMITTER: Yoon CI
PROVIDER: S-EPMC6709902 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Yoon Chang Ik CI Ahn Sung Gwe SG Bae Soong June SJ Shin Yun Jin YJ Cha Chihwan C Park So Eun SE Lee Ji-Hyung JH Ooshima Akira A Lee Hye Sun HS Yang Kyung-Min KM Kim Seong-Jin SJ Park Seok Hee SH Jeong Joon J
PloS one 20190826 8
<h4>Background</h4>A20 protein has ubiquitin-editing activities and acts as a key regulator of inflammation and immunity. Previously, our group showed that A20 promotes tumor metastasis through multi-monoubiquitylation of SNAIL1 in basal-like breast cancer. Here, we investigated survival outcomes in patients with breast cancer according to A20 expression.<h4>Patients and methods</h4>We retrospectively collected tumor samples from patients with breast cancer. Immunohistochemistry (IHC) with an A2 ...[more]