An Equine Wound Model to Study Effects of Bacterial Aggregates on Wound Healing.
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ABSTRACT:
SUBMITTER: Jorgensen E
PROVIDER: S-EPMC6709944 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Publications
An Equine Wound Model to Study Effects of Bacterial Aggregates on Wound Healing.
Jørgensen Elin E Bay Lene L Skovgaard Lene T LT Bjarnsholt Thomas T Jacobsen Stine S
Advances in wound care 20190821 10
<b>Objective:</b> Relevant animal models to study effects of bacterial aggregates on wound healing are lacking. We aimed at establishing an equine wound model with bacterial aggregates to investigate the impact of bacterial inoculation on normal (thorax) and impaired (limb) wound healing. <b>Approach:</b> Wounds were created on three limbs and both thorax sides of six horses. Twelve out of 20 wounds per horse were inoculated with 10<sup>4</sup> <i>Staphylococcus aureus</i> and 10<sup>5</sup> <i> ...[more]
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