Ontology highlight
ABSTRACT:
SUBMITTER: Graw J
PROVIDER: S-EPMC6710221 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Human genetics 20190327 8-9
Mouse mutants are a long-lasting, valuable tool to identify genes underlying eye diseases, because the absence of eyes, very small eyes and severely affected, cataractous eyes are easily to detect without major technical equipment. In mice, actually 145 genes or loci are known for anophthalmia, 269 for microphthalmia, and 180 for cataracts. Approximately, 25% of the loci are not yet characterized; however, some of the ancient lines are extinct and not available for future research. The phenotype ...[more]