Ontology highlight
ABSTRACT:
SUBMITTER: Hellwege JN
PROVIDER: S-EPMC6710266 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Nature communications 20190826 1
Chronic kidney disease (CKD), defined by low estimated glomerular filtration rate (eGFR), contributes to global morbidity and mortality. Here we conduct a transethnic Genome-Wide Association Study of eGFR in 280,722 participants of the Million Veteran Program (MVP), with replication in 765,289 participants from the Chronic Kidney Disease Genetics (CKDGen) Consortium. We identify 82 previously unreported variants, confirm 54 loci, and report interesting findings including association of the sickl ...[more]