Microglia in Retinal Degeneration.
Ontology highlight
ABSTRACT:
SUBMITTER: Rashid K
PROVIDER: S-EPMC6710350 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Publications
Microglia in Retinal Degeneration.
Rashid Khalid K Akhtar-Schaefer Isha I Langmann Thomas T
Frontiers in immunology 20190820
The retina is a complex tissue with multiple cell layers that are highly ordered. Its sophisticated structure makes it especially sensitive to external or internal perturbations that exceed the homeostatic range. This necessitates the continuous surveillance of the retina for the detection of noxious stimuli. This task is mainly performed by microglia cells, the resident tissue macrophages which confer neuroprotection against transient pathophysiological insults. However, under sustained patholo ...[more]
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