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Ecological interventions to prevent and manage zoonotic pathogen spillover.


ABSTRACT: Spillover of a pathogen from a wildlife reservoir into a human or livestock host requires the pathogen to overcome a hierarchical series of barriers. Interventions aimed at one or more of these barriers may be able to prevent the occurrence of spillover. Here, we demonstrate how interventions that target the ecological context in which spillover occurs (i.e. ecological interventions) can complement conventional approaches like vaccination, treatment, disinfection and chemical control. Accelerating spillover owing to environmental change requires effective, affordable, durable and scalable solutions that fully harness the complex processes involved in cross-species pathogen spillover. This article is part of the theme issue 'Dynamic and integrative approaches to understanding pathogen spillover'.

SUBMITTER: Sokolow SH 

PROVIDER: S-EPMC6711299 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature

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Ecological interventions to prevent and manage zoonotic pathogen spillover.

Sokolow Susanne H SH   Nova Nicole N   Pepin Kim M KM   Peel Alison J AJ   Pulliam Juliet R C JRC   Manlove Kezia K   Cross Paul C PC   Becker Daniel J DJ   Plowright Raina K RK   McCallum Hamish H   De Leo Giulio A GA  

Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20190812 1782


Spillover of a pathogen from a wildlife reservoir into a human or livestock host requires the pathogen to overcome a hierarchical series of barriers. Interventions aimed at one or more of these barriers may be able to prevent the occurrence of spillover. Here, we demonstrate how interventions that target the ecological context in which spillover occurs (i.e. ecological interventions) can complement conventional approaches like vaccination, treatment, disinfection and chemical control. Accelerati  ...[more]

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