Ontology highlight
ABSTRACT:
SUBMITTER: Wei X
PROVIDER: S-EPMC6711367 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Wei Xiaoli X Ran Danni D Campeau Anaamika A Xiao Crystal C Zhou Jiarong J Dehaini Diana D Jiang Yao Y Kroll Ashley V AV Zhang Qiangzhe Q Gao Weiwei W Gonzalez David J DJ Fang Ronnie H RH Zhang Liangfang L
Nano letters 20190611 7
Infections caused by multidrug-resistant Gram-negative bacteria have emerged as a major threat to public health worldwide. The high mortality and prevalence, along with the slow pace of new antibiotic discovery, highlight the necessity for new disease management paradigms. Here, we report on the development of a multiantigenic nanotoxoid vaccine based on macrophage membrane-coated nanoparticles for eliciting potent immunity against pathogenic <i>Pseudomonas aeruginosa</i>. The design of this bio ...[more]