Ontology highlight
ABSTRACT:
SUBMITTER: Browne P
PROVIDER: S-EPMC6711601 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Browne P P Kleinstreuer N C NC Ceger P P Deisenroth C C Baker N N Markey K K Thomas R S RS Judson R J RJ Casey W W
Reproductive toxicology (Elmsford, N.Y.) 20180908
A systematic literature review was conducted to identify Hershberger bioassays for ∼3200 chemicals including those used to validate the OECD/US EPA guideline assay, US EPA's chemicals screened for endocrine activity, and the library of chemicals run in US EPA 's ToxCast in vitro assays. For 134 chemicals that met pre-defined criteria, experimental results were extracted into a database used to characterize uncertainty in results and evaluate the concordance of the Hershberger assay with other in ...[more]