A 23 gene-based molecular prognostic score precisely predicts overall survival of breast cancer patients.
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ABSTRACT:
SUBMITTER: Shimizu H
PROVIDER: S-EPMC6711850 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Publications
A 23 gene-based molecular prognostic score precisely predicts overall survival of breast cancer patients.
Shimizu Hideyuki H Nakayama Keiichi I KI
EBioMedicine 20190726
<h4>Background</h4>Although many prognosis-predicting molecular scores for breast cancer have been developed, they are applicable to only limited disease subtypes. We aimed to develop a novel prognostic score that is applicable to a wider range of breast cancer patients.<h4>Methods</h4>We initially examined The Cancer Genome Atlas breast cancer cohort to identify potential prognosis-related genes. We then performed a meta-analysis of 36 international breast cancer cohorts to validate such genes. ...[more]
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