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Patient Characteristics and General Practitioners' Advice to Stop Statins in Oldest-Old Patients: a Survey Study Across 30 Countries.


ABSTRACT: BACKGROUND:Statins are widely used to prevent cardiovascular disease (CVD). With advancing age, the risks of statins might outweigh the potential benefits. It is unclear which factors influence general practitioners' (GPs) advice to stop statins in oldest-old patients. OBJECTIVE:To investigate the influence of a history of CVD, statin-related side effects, frailty and short life expectancy, on GPs' advice to stop statins in oldest-old patients. DESIGN:We invited GPs to participate in this case-based survey. GPs were presented with 8 case vignettes describing patients >?80 years using a statin, and asked whether they would advise stopping statin treatment. MAIN MEASURES:Cases varied in history of CVD, statin-related side effects and frailty, with and without shortened life expectancy (?80 years. Overall, and within all countries, cancer-related short life expectancy was the strongest independent predictor of GPs' advice to stop statins.

SUBMITTER: van der Ploeg MA 

PROVIDER: S-EPMC6711940 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature

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Patient Characteristics and General Practitioners' Advice to Stop Statins in Oldest-Old Patients: a Survey Study Across 30 Countries.

van der Ploeg Milly A MA   Streit Sven S   Achterberg Wilco P WP   Beers Erna E   Bohnen Arthur M AM   Burman Robert A RA   Collins Claire C   Franco Fabio G FG   Gerasimovska-Kitanovska Biljana B   Gintere Sandra S   Gomez Bravo Raquel R   Hoffmann Kathryn K   Iftode Claudia C   Peštić Sanda Kreitmayer SK   Koskela Tuomas H TH   Kurpas Donata D   Maisonneuve Hubert H   Mallen Christan D CD   Merlo Christoph C   Mueller Yolanda Y   Muth Christiane C   Petrazzuoli Ferdinando F   Rodondi Nicolas N   Rosemann Thomas T   Sattler Martin M   Schermer Tjard T   Šter Marija Petek MP   Švadlenková Zuzana Z   Tatsioni Athina A   Thulesius Hans H   Tkachenko Victoria V   Torzsa Péter P   Tsopra Rosy R   Tuz Canan C   Vaes Bert B   Viegas Rita P A RPA   Vinker Shlomo S   Wallis Katharine A KA   Zeller Andreas A   Gussekloo Jacobijn J   Poortvliet Rosalinde K E RKE  

Journal of general internal medicine 20190116 9


<h4>Background</h4>Statins are widely used to prevent cardiovascular disease (CVD). With advancing age, the risks of statins might outweigh the potential benefits. It is unclear which factors influence general practitioners' (GPs) advice to stop statins in oldest-old patients.<h4>Objective</h4>To investigate the influence of a history of CVD, statin-related side effects, frailty and short life expectancy, on GPs' advice to stop statins in oldest-old patients.<h4>Design</h4>We invited GPs to part  ...[more]

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