Dataset Information

Correlation between chest radiographic findings and clinical features in hospitalized children with Mycoplasma pneumoniae pneumonia.

ABSTRACT:

Background

Radiologic evaluation of children with Mycoplasma pneumoniae is important for diagnosis and management.

Objective

To investigate the correlation between chest radiographic findings and the clinical features in children with Mycoplasma pneumoniae pneumonia.

Materials and methods

This study included 393 hospitalized children diagnosed with M. pneumoniae pneumonia between January 2000 and August 2016. Their clinical features and chest radiographs were reviewed. Radiographic findings were categorized and grouped as consolidation group (lobar or segmental consolidation) and non-consolidation group (patchy infiltration, localized reticulonodular infiltration, or parahilar peribronchial infiltration).

Results

Lobar or segmental consolidation (37%) was the most common finding, followed by parahilar or peribronchial infiltration (27%), localized reticulonodular infiltration (21%) and patchy infiltration (15%). The consolidation group was more frequently accompanied by pleural effusions (63%), compared to the non-consolidation group (16%). Compared with patients in the non-consolidation group, those in the consolidation group were associated with a significantly higher rate of hypoxia, tachypnea, tachycardia, extrapulmonary manifestations, prolonged fever, and longer periods of anti-mycoplasma therapy and hospitalization. Lobar or segmental consolidation was significantly more frequent in children ?5 years old (44%) compared with children 2-5 years old (34%) and <2 years old (13%). Parahilar peribronchial infiltration was significantly more frequent in children <2 years old (56%) compared with children 2-5 years old (32%) and ?5 years old (18%).

Conclusion

The chest radiographic findings of children with M. pneumoniae pneumonia correlate well with the clinical features. Consolidative lesions were frequently observed in older children and were associated with more severe clinical features.

SUBMITTER: Cho YJ

PROVIDER: S-EPMC6713385 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature

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Publications

Correlation between chest radiographic findings and clinical features in hospitalized children with Mycoplasma pneumoniae pneumonia.

Cho Yeon Jin YJ Han Mi Seon MS Kim Woo Sun WS Choi Eun Hwa EH Choi Young Hun YH Yun Ki Wook KW Lee SeungHyun S Cheon Jung-Eun JE Kim In-One IO Lee Hoan Jong HJ

PloS one 20190828 8

<h4>Background</h4>Radiologic evaluation of children with Mycoplasma pneumoniae is important for diagnosis and management.<h4>Objective</h4>To investigate the correlation between chest radiographic findings and the clinical features in children with Mycoplasma pneumoniae pneumonia.<h4>Materials and methods</h4>This study included 393 hospitalized children diagnosed with M. pneumoniae pneumonia between January 2000 and August 2016. Their clinical features and chest radiographs were reviewed. Radi ...[more]

PMID: 31461462

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Project description:BackgroudThe current diagnostic criteria for refractory Mycoplasma pneumoniae pneumonia (RMPP) among Mycoplasma pneumoniae Pneumonia (MPP) are insufficient for early identification, and potentially delayed appropriate treatment. This study aimed to develop an effective individualized diagnostic prediction nomogram for pediatric RMPP.MethodsA total of 517 hospitalized children with MPP, including 131 with RMPP and 386 without RMPP (non-RMPP), treated at Lianyungang Maternal and Child Health Care Hospital from January 2018 to December 2021 were retrospectively enrolled as a development (modeling) cohort to construct an RMPP prediction nomogram. Additionally, 322 pediatric patients with MPP (64 with RMPP and 258 with non-RMPP, who were treated at the Affiliated Hospital of Xuzhou Medical University from June 2020 to May 2022 were retrospectively enrolled as a validation cohort to assess the prediction accuracy of model. Univariable and multivariable logistic regression analyses were used to identify RMPP risk factors among patients with MPP. Nomogram were generated based on these risk factors using the rms package of R, and the predictive performance was evaluated based on receiver operating characteristic (ROC) curves and using decision curve analysis (DCA).ResultsMultivariate analysis revealed five significant independent predictors of RMPP among patients with MPP: age (hazard ratio [HR] 1.16, 95% confidence interval [CI] 1.08-1.33, P = 0.038), fever duration (HR 1.34, 95%CI 1.20-1.50, P < 0.001), lymphocyte count (HR 0.45, 95%CI 0.23-0.89, P = 0.021), serum D-dimer (D-d) level (HR 1.70, 95%CI 1.16-2.49, P = 0.006), and pulmonary imaging score (HR 5.16, 95%CI 2.38-11.21, P < 0.001). The area under the ROC curve was 90.7% for the development cohort and 96.36% for the validation cohort. The internal and external verification calibration curves were almost linear with slopes of 1, and the DCA curve revealed a net benefit with the final predictive nomogram.ConclusionThis study proposes a predictive nomogram only based on five variables. The nomogram can be used for early identification of RMPP among pediatric patients with MPP, thereby facilitating more timely and effective intervention.

Dataset Information

Correlation between chest radiographic findings and clinical features in hospitalized children with Mycoplasma pneumoniae pneumonia.

Background

Objective

Materials and methods

Results

Conclusion

Publications

Correlation between chest radiographic findings and clinical features in hospitalized children with Mycoplasma pneumoniae pneumonia.

Similar Datasets

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