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Short interpregnancy interval as a risk factor for preterm birth in non-Hispanic Black and White women in California.


ABSTRACT: OBJECTIVE:Short interpregnancy interval (IPI) is associated with adverse pregnancy outcomes, including preterm birth (PTB ?1.5 million California live births, we examined frequencies of short IPI between racial/ethnic groups and estimated risks by multivariable logistic regression for spontaneous PTB. We expanded the study to births 1991-2012 and utilized a "within-mother" approach to permit methodologic inquiry about residual confounding. RESULTS:NHB women had higher frequency (7.6%) of short IPI than non-Hispanic White (NHW) women (4.4%). Adjusted odds ratios for PTB and short IPI were 1.64 (95% CI 1.54, 1.76) for NHW and 1.49 (1.34, 1.65) for NHB. Using within-mother analysis did not produce substantially different results. CONCLUSIONS:Short IPI is associated with PTB but does not explain risk disparity between NHWs and NHBs.

SUBMITTER: Lonhart JA 

PROVIDER: S-EPMC6713584 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature

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Short interpregnancy interval as a risk factor for preterm birth in non-Hispanic Black and White women in California.

Lonhart Julia A JA   Mayo Jonathan A JA   Padula Amy M AM   Wise Paul H PH   Stevenson David K DK   Shaw Gary M GM  

Journal of perinatology : official journal of the California Perinatal Association 20190617 9


<h4>Objective</h4>Short interpregnancy interval (IPI) is associated with adverse pregnancy outcomes, including preterm birth (PTB < 37 weeks GA). We investigated whether short IPI (< 6 months) contributes to the higher PTB frequency among non-Hispanic Blacks (NHB).<h4>Study design</h4>Using a linked birth cohort > 1.5 million California live births, we examined frequencies of short IPI between racial/ethnic groups and estimated risks by multivariable logistic regression for spontaneous PTB. We e  ...[more]

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